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Cambio de paradigma: el cannabis medicinal puede proteger las neuronas
Médicos especialistas en cannabis medicinal destacaron que “el paradigma del ‘cannabis quema neuronas’ está cambiando a ‘el cannabis puede hasta proteger neuronas” y, específicamente en el caso del Alzheimer, los cannabinoides presentes en la marihuana “actúan sobre todos los objetivos del tratamiento (farmacológico convencional) de la enfermedad”.
Los beneficios del cannabis medicinal en enfermedades propias de los adultos mayores, en especial los cuidados paliativos, el tratamiento del dolor y las demencias fue uno de los ejes temáticos abordados en las diferentes charlas y conferencias de la segunda Expo Cannabis que concluye este domingo en La Rural.
“El uso de cannabis tiene una potencial utilización muy importante sobre todo en esta etapa de la vida, en la tercera edad”, dijo el médico clínico e integrante de la Red de Profesionales para el estudio del Cannabis (Reprocann), Nicolás Di Biase durante la conferencia “Tercera edad y cannabis medicinal”.
Es que el paciente gerontológico se caracteriza por “una alta prevalencia y acumulación de enfermedades crónicas” que a su vez redundan en una “polimedicación o polifarmacia”, todo lo cual se traduce en “un alto gasto económico en salud” que coincide con una etapa de “reducción de ingresos, muchas veces, cuando la persona se jubila”.
“Cuando uno llega a 65 o 70 años habitualmente acumula hipertensión, diabetes, artrosis, diferentes problemáticas crónicas que hacen que la calidad de vida se vea deteriorada”, manifestó.
“Pero además existe este problemón que es que yo tengo una persona cuyo hígado, riñones e intestinos tienen 80 años y aun así está tomando 12 medicamentos: es una lógica que no cierra muy bien”, agregó.
Por eso, “cuando hablamos de que el cannabis puede ayudarnos a reducir la cantidad de medicamentos es algo positivo para este grupo etario” tanto en términos de calidad de vida como de reducción del gasto en medicamentos.
Además, durante esta etapa de la vida “también se generan algunos cambios en el sistema endocannabinoide”, conformado por receptores cannabinoides endógenos involucrados en una serie de procesos fisiológicos -como el apetito, el dolor, el humor- que sufren “una disminución importante a partir de los 65 años” y que pueden ser estimulados exógenamente con el uso de cannabis medicinales.
“El paradigma del ‘cannabis rompe y quema neuronas’, está cambiando a ‘el cannabis puede hasta proteger neuronas’ porque puede evitar que se oxiden tan rápido y las neuronas oxidadas generan demencia”, dijo.
Adicionalmente, Di Biase apuntó que “el cannabis es una herramienta superadora no farmacológica -en el sentido sintético de la palabra-, para el manejo de problemas de salud frecuentes y de difícil control en adultos mayores” tales como el dolor crónico, el insomnio y la excitación psicomotriz propia de los estadios avanzados de las demencias.
“Hoy podemos encontrarnos con tres variantes o quimiotipos de cannabis con diferentes perfiles de respuesta: los ricos en THC (tipo 1), los ricos en CBD (tipo 3) o con fórmula balanceada entre ambos (tipo2)”, explicó.
Las variantes con más THC funcionan bien como “relajante muscular” y es un psicoactivo con beneficios para “el paciente con deterioro cognitivo”, mientras que “el antisicótico bien claro de los fitocannabinoides es el CBD, un gran potencial contra la ansiedad, la excitación psicomotriz y la demencia”.
“Ambos funcionan contra los vómitos y el sedativo es sobre todo el THC, pero los dos tienen implicancias antagónicas sobre los procesos cardiovasculares: unos causan bradicardia (poca frecuencia cardíaca) y otros taquicardia”, agregó.
Por eso, “la dosificación es altamente individual y requiere titulación”, es decir, ir de mayor a menor, registrando los efectos hasta encontrar la dosis adecuada.
Y aunque “la principal aplicación que tiene en el mundo el cannabis medicinal es el tratamiento del dolor crónico”, en Argentina aún no hay medicamentos fitoterápicos a base de marihuana aprobados para este uso.
“No es una indicación contemplada en el sistema de salud argentino, es decir que hoy ningún médico puede recetar un producto de cannabis que vos puedas ir a una farmacia a comprarlo”, explicó.
Añadió que “por el momento la única aplicación contemplada es la epilepsia refractaria, pero tenemos es una salida muy buena a la falta de acceso que es la de cultivar tu propio cannabis como para poder realizar tu propia medicina”.
«El cannabis es una medicación segura con baja tasa de dependencia, una dosis letal casi inexistente y efectos adversos leves»
NICOLÁS DE BIASE, MÉDICO – REPROCANN
Adicionalmente, el médico aseguró que el cannabis medicinal es “una medicación segura” con “baja tasa de dependencia, una dosis letal casi inexistente y efectos adversos leves” que, no obstante, “requiere acompañamiento médico”.
A su turno, el neurólogo e investigador Alejandro Andersson afirmó que, para el caso de las personas con Alzheimer, la investigación científica demuestra que el tratamiento con cannabis medicinal “mejora las funciones cognitivas, conductuales y musculares” que se ven alteradas típicamente en esta enfermedad.
“Los cannabinoides actúan en los procesos de señalización (celular), de dolor, de procesamiento anormal del (péptido) beta amiloide y de la proteína tau, de la neuroinflamación, de la excitotoxicidad, del estrés oxidativo, de la disfunción mitocondrial: todos objetivos del tratamiento de la enfermedad de Alzheimer”, dijo Andersson, quien dirige el Instituto de Neurología de Buenos Aires (INBA).
El cannabis medicinal “modula la neurotransmisión, mejorando la sinapsis entre las neuronas y, por lo tanto, mejora la memoria”
ALEJANDRO ANDERSSON, NEURÓLOGO – INBA
Pero además, el cannabis medicinal “modula la neurotransmisión, mejorando la sinapsis entre las neuronas y, por lo tanto, “mejora la memoria”.
“También los trastornos de conducta, son mejorados en particular por el CBD y hay muchos trastornos de conducta en la enfermedad de Alzheimer”, apuntó.
Además, el cannabis tiene un efecto benéfico sobre el sueño que es importante que sea de calidad para no facilitar la progresión de la enfermedad: “el CBD mejora el sueño REM profundo y el THC disminuye las pesadillas y facilita la conciliación rápida”.
Además, el CBD “disminuye la sarcopenia” propia de los adultos mayores que se ve acentuada en los pacientes con Alzheimer, “porque protege y previene la pérdida de masa muscular”.
“Dirigirse al sistema endocannabonoide es una estrategia sumamente prometedora para el tratamiento de la enfermedad de Alzheimer”, concluyó.
Fuente: Telam
Para leer
La Virgen del Milagro en el Polo Sur: El salteño que unió fe y patria en la Antártida
Un militar salteño unió la fe del Milagro con la historia antártica argentina. En 1965, el rosarino Jorge Edgar Leal, al mando de una expedición al Polo Sur, no solo izó la bandera nacional, sino que también dejó una réplica de la imagen de la Virgen del Milagro en el rincón más austral del planeta.
En el marco de una nueva celebración del Señor y la Virgen del Milagro, patronos de Salta, es oportuno recordar la hazaña de un militar salteño que llevó la devoción provincial al rincón más austral del planeta. El rosarino Jorge Edgar Leal, al mando de la histórica expedición «Operación 90», dejó un legado imborrable que fusiona la identidad salteña con la historia antártica argentina.
El 10 de diciembre de 1965, después de 48 días de viaje y 1.450 kilómetros recorridos en un contexto de temperaturas extremas y condiciones climáticas adversas, la expedición de Leal llegó al Polo Sur. En ese punto, izó con orgullo la bandera argentina y, en un acto que «salteñizó» la proeza, dejó una réplica de la imagen de la Virgen del Milagro en la meseta antártica.
Esta gesta, que no aparece en las memorias del propio Leal, fue reportada en una breve crónica del diario El Tribuno de Salta, destacando que «ahora los salteños pueden decir que su imagen patrona vela por la patria, desde el mismo Polo Sur».
Un viaje a corazón helado: La travesía de la «Operación 90»
La expedición, que partió desde la base argentina Manuel Belgrano, enfrentó desafíos inmensos. Leal, en sus crónicas publicadas en «Memorias de un antártico», relató las dificultades de la marcha final con 30 grados bajo cero y una densa capa de nubes que impedía la orientación.
Fue gracias al sargento ayudante Adolfo Oscar Moreno, un topógrafo de la misión, que lograron aprovechar un breve claro en el cielo para determinar su posición y continuar el rumbo. La llegada al Polo fue confirmada al divisar las instalaciones de la base norteamericana Amundsen-Scott, una señal inequívoca de su éxito.
El vehículo que transportaba a Leal y a la imagen de la Virgen del Milagro llevaba el nombre «Salta» en su honor, un guiño a la tierra natal del militar. Tras la llegada, Leal elevó el mástil de la bandera argentina y se comunicó por radio con las autoridades en Buenos Aires. Posteriormente, el equipo posó para la foto que inmortalizaría el logro, un momento de victoria en el que las nubes se disiparon, como si la misma naturaleza hubiera querido ser testigo de la proeza.
La historia de Jorge Edgar Leal es un recordatorio de cómo la fe y la devoción, tan arraigadas en la cultura salteña, pueden ser parte de las mayores hazañas humanas, uniendo el fervor del Milagro con la inmensidad del continente blanco.
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“Quería terminar con el dolor”: Flor cuenta su experiencia tras intentar suicidarse
En el marco de septiembre, mes dedicado a la prevención del suicidio, Flor, una joven de 35 años, decidió compartir por primera vez su experiencia personal con ideaciones suicidas. Su testimonio revela el camino desde la oscuridad y la desesperanza hasta la búsqueda de ayuda profesional, el acompañamiento familiar y espiritual, y la reconstrucción de su vida.
Con el inicio de septiembre, mes destinado a la concientización y prevención del suicidio, los especialistas insisten en la importancia de abrir el diálogo sobre un tema que sigue siendo un tabú en la sociedad argentina. Hablar de pensamientos suicidas, acompañamiento familiar y salud mental no es sencillo, pero se trata de una cuestión de vida o muerte. En este marco, Flor, una mujer de 35 años, comparte por primera vez su experiencia personal, con la intención de ofrecer una guía de esperanza y mostrar que pedir ayuda es posible y necesario.
Flor recordó las ocasiones en que intentó quitarse la vida. “Tenía todo lo material y familiar que uno podría desear, pero me sentía vacía, incompleta. Nada llenaba ese vacío”, confesó. La joven relató cómo heridas de la infancia no resueltas y la acumulación de emociones reprimidas contribuyeron a sumergirla en un estado de profunda tristeza y desesperanza.
Suicidio: un tema que incomoda pero que debe ser tratado sin rodeos ni prejuicios
“Muchas veces creemos que podemos solos, que solo con voluntad podremos superar la oscuridad. No es así”, explicó. En su experiencia, buscar ayuda profesional, terapias psicológicas y, cuando fue necesario, tratamiento psiquiátrico, fueron herramientas esenciales para reconstruirse.
“Pedir ayuda me permitió salir adelante; hay esperanza incluso en los momentos más oscuros.”
Enfatizó que identificar que se necesita ayuda es el primer paso para superar la crisis. “Cuando uno atraviesa ideaciones suicidas, no puede salir adelante solo. La asistencia profesional, acompañada del apoyo familiar y comunitario, es fundamental”, subrayó. Recomendó iniciar el diálogo incluso de formas indirectas: un mensaje, una canción, un video o un reel que refleje lo que se siente puede ser un primer paso para pedir ayuda.
“Decirle a alguien ‘me siento así’ puede salvar vidas. Muchos jóvenes piensan que están solos, pero no es cierto. Siempre hay recursos disponibles: psicólogos, hospitales, iglesias, líneas de asistencia”, agregó.
“La terapia y el acompañamiento profesional me enseñaron a encontrar sentido y propósito en mi vida.”
En su relato, destacó también el rol de la fe como complemento a la atención profesional. La espiritualidad, explicó, le permitió encontrar un eje de contención emocional y sentido de vida: “Mi fe y mi relación con Dios fueron un pilar. La terapia y el acompañamiento psicológico me dieron herramientas, pero la fe me sostuvo y me restauró desde adentro”.
Asimismo, Flor advirtió que el tabú sobre la salud mental no solo existe en la sociedad, sino en los hogares. Muchos padres, por desconocimiento, minimizan los síntomas de angustia o tristeza profunda de sus hijos. “Frases como ‘no te falta nada’ o ‘eso es para locos’ generan muros en lugar de puentes. La salud mental no se mide en bienes materiales; requiere escucha, acompañamiento y contención emocional”, aseguró.
El testimonio de Flor también resaltó señales de alerta que los padres y familiares pueden observar como por ejemplo; aislamiento, descuido personal, cambios drásticos de conducta, consumo de sustancias o pérdida de motivación. Identificar estos indicadores a tiempo puede marcar la diferencia entre la vida y la muerte.
“Compartir lo que sentimos, aunque sea con un mensaje o un gesto, nos conecta y nos ayuda a superar la tristeza.”
Mensaje de esperanza
Flor dio un mensaje para quienes atraviesan momentos similares: “No están solos. Buscar ayuda no es un signo de debilidad, es un grito de vida. Se puede salir adelante, reconstruirse y encontrar propósito y sentido en la existencia”.
Su historia evidenció que la prevención del suicidio requiere diálogo abierto, acompañamiento profesional, comprensión familiar y, en muchos casos, apoyo espiritual. “Romper el tabú, hablar con responsabilidad y ofrecer contención puede salvar vidas”, concluyó.
“Con fe, apoyo y herramientas adecuadas, es posible transformar la oscuridad en fuerza y reconstrucción personal.”
Con su testimonio, esta joven metanense, demostró que aunque el camino sea difícil, hay salida. Su historia no solo visibiliza el dolor que enfrentan quienes atraviesan ideaciones suicidas, sino también las herramientas de recuperación y la importancia de un entorno que escuche y acompañe.
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Suicidio: un tema que incomoda pero que debe ser tratado sin rodeos ni prejuicios
En su columna semanal, el psicólogo Lic. Fernando Serrano Urdanibia (MP 1894) aborda el suicidio como uno de los tabúes más fuertes de nuestra sociedad y plantea la necesidad de hablar del tema con responsabilidad, en el marco del mes dedicado a su prevención.
El suicidio sigue siendo, en pleno siglo XXI, un tema que incomoda, se esquiva y en muchos ámbitos se evita mencionar. Hablar de él implica atravesar un muro cultural y social que lo ha convertido en un verdadero tabú, reforzado por prejuicios, temores y silencios que no solo no resuelven el problema, sino que lo profundizan.
Durante años, distintos asuntos ocuparon el lugar de lo innombrable. La sexualidad, por ejemplo, estuvo rodeada de prohibiciones hasta que, poco a poco, se comenzó a tratar con mayor apertura. Sin embargo, la muerte continúa siendo un terreno lleno de restricciones, y dentro de ella, la decisión de poner fin a la propia vida aparece como uno de los temas más difíciles de afrontar.
En el marco del mes amarillo dedicado a la prevención del suicidio, el psicólogo Fernando Serrano Urdanibia plantea la necesidad de abordar este fenómeno de manera seria, responsable y sin rodeos, acompañado por testimonios como el de Flor, una mujer que atravesó un intento de suicidio y hoy decidió compartir su experiencia como forma de tender una mano a quienes aún buscan ayuda.
“El silencio puede incomodar. El silencio, incluso, puede llegar a matar”
Uno de los factores más complejos es el silencio. “El silencio puede incomodar y, en ciertos casos, puede llegar a matar”, explica Serrano Urdanibia. La sociedad argentina habla muy poco de suicidio, y cuando lo hace suele ser desde la culpa, la vergüenza o el desconocimiento. En muchas familias, frente a un fallecimiento por esta causa, se escucha todavía: “Mejor no hables de eso” o “Inventá otra cosa”.
Ese ocultamiento priva a quienes atraviesan pensamientos suicidas de un espacio donde expresar su dolor. Según la Organización Mundial de la Salud (OMS), hablar del tema con responsabilidad no induce al acto, sino que abre la posibilidad de que alguien en crisis busque ayuda.
“Mientras evitamos el tema, el suicidio mata a más de un millón de personas al año en el mundo”
Las estadísticas son contundentes; cada año, más de un millón de personas en el mundo mueren por suicidio. Se trata de una cifra que supera a la de los accidentes de tránsito o a la suma de todas las muertes violentas. Sin embargo, a diferencia de otros problemas sociales, el suicidio rara vez ocupa un lugar en la agenda pública.
Prejuicios que sostienen el tabú
Algunos de los argumentos más repetidos para mantener el silencio son:
- “Hablar de suicidio puede alentar a las personas”: en realidad, hacerlo de manera responsable permite abrir un espacio de reflexión.
- “Quien dice que va a suicidarse no lo hará”: cada pedido de ayuda debe tomarse con seriedad.
- “El suicida tiene todo decidido”: en la mayoría de los casos existe ambivalencia; una palabra de apoyo puede cambiar el desenlace.
- “El suicidio es hereditario”: lo que influyen son factores de personalidad, contexto y salud emocional, no la herencia biológica.
Los estudios señalan que testimonios de personas que atravesaron situaciones de riesgo y lograron pedir ayuda pueden tener un efecto positivo de imitación, fortaleciendo la esperanza y la decisión de vivir.
“Pedir ir al psicólogo no es un capricho. Es un pedido de escucha profesional, libre de juicio”
El tabú en el hogar
El problema no está solo en la sociedad, también en los hogares. “Cuando un hijo pide ir al psicólogo, muchas veces se le responde: ‘¿Para qué, si no te falta nada?’ o ‘Eso es para locos’”, señala Serrano Urdanibia. Estas respuestas levantan muros en lugar de abrir caminos de contención.
El bienestar emocional no depende de tener casa o alimento, sino de sentirse acompañado y comprendido. Negar la ayuda profesional bajo la idea de que “es cuestión de voluntad” profundiza la soledad y, en muchos casos, puede agravar el sufrimiento.
“Ese silencio es una segunda muerte. Convierte el hecho en un fantasma del que nadie habla, pero que todos sienten”
El escenario más doloroso se da cuando el pedido de ayuda no fue escuchado y la persona decide quitarse la vida. En muchos casos, el hecho se oculta bajo la palabra “accidente” o se evita mencionarlo. Ese silencio, calificado por especialistas como “una segunda muerte”, no permite elaborar el duelo ni reconocer la importancia de la salud mental.
Hablar no devuelve la vida de quien ya no está, pero sí puede salvar a quienes aún buscan ser comprendidos.
La fe ocupa un lugar central en numerosas familias. La religión puede brindar acompañamiento y comunidad, pero no debe reemplazar la atención profesional. “Rezar puede dar alivio, pero no sustituye a la intervención clínica necesaria”, sostiene el especialista. La espiritualidad y la psicología, en cambio, pueden complementarse.
“Hablar del suicidio con respeto y responsabilidad no lo promueve, lo previene”
Hablar para prevenir
El consenso entre especialistas es; hablar de suicidio no lo fomenta, lo previene. Callar, en cambio, alimenta la oscuridad. El suicidio no se enfrenta con silencios, sino con escucha, acompañamiento y políticas públicas que garanticen atención accesible.
Serrano Urdanibia concluye: “Pedir ayuda no es debilidad, es un acto de vida. El tabú del suicidio debe romperse con información y diálogo. Que no se lo hable, no quiere decir que deja de existir”.
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