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QUIÉN ES LA CIENTÍFICA ARGENTINA QUE BUSCA REVERTIR EL AUTISMO

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UN EQUIPO DE INVESTIGADORES LOGRÓ REVERTIR, EN RATONES, CIERTAS CONDUCTAS RELACIONADAS CON EL AUTISMO. SIN EMBARGO, LAS CAUSAS MÁS PROFUNDAS AÚN SIGUEN SIENDO UN ROMPECABEZAS SIN RESOLVER.

El 1% de la población mundial se encuentra dentro del Trastorno del Espectro Autista (TEA). En la Argentina se estima que cerca de 400.000 personas responden a este diagnóstico.

Este trastorno se refiere a un grupo de modificaciones del neurodesarrollo que se identifican por alteraciones en la comunicación social y en los patrones de comportamiento e intereses, particularmente, está caracterizado por generar un déficit en la sociabilidad del sujeto que lo padece.

Según estudios epidemiológicos recogidos por la Organización Mundial de la Salud realizados en los últimos 50 años, la prevalencia mundial de estos trastornos parece estar aumentando. Hay diferentes explicaciones posibles para este aparente incremento: una mayor concienciación, la ampliación de los criterios diagnósticos, mejores herramientas diagnósticas y más difusión.

Sin embargo, las causas que subyacen a la condición aún no son claras: la evidencia científica más reciente parece apuntar a una combinación de factores ambientales y sociales con ciertas predisposiciones biológicas y neurales. De eso se encarga Amaicha Depino, neurocientífica investigadora del Conicet y doctora en biología por la Universidad Buenos Aires.

«Hoy sabemos que son las susceptibilidades biológicas las que se refuerzan con la interacción social. Si bien no sabemos cuáles son exactamente, sí sabemos que como en toda enfermedad y condición humana, hay un factor biológico», dice Depino

Solución argentina

El trabajo de esta investigadora se fundamenta en la creación de modelos animales del TEA, específicamente ratones, porque estos animales son naturalmente sociables y curiosos lo que facilita que los investigadores vean los cambios que pueden suceder.

En este caso, los científicos locales están trabajando sobre una reciente hipótesis que relaciona el uso de ácido valproico (un anticonvulsivo bastante común) en la etapa prenatal con ciertas características propias del TEA. En los ratones se da una sola inyección en la mitad de la preñez, que es cuando cierra el tubo neural, un momento clave para el desarrollo del sistema nervioso.

«En los ratones tratados se observó menor sociabilidad y ahora queremos ver qué sucedía si, al momento del destete, enriquecemos su vida social», explica la científica. Para esto, los investigadores crearon dos grupos de ratones, uno que fue sometido al ácido valproico y, en efecto, desarrolló características propias del TEA.

Sin embargo, los científicos sometieron a estos ratones a una fuerte estimulación temprana para poner a prueba la hipótesis de que así puede revertirse algunos aspectos del trastorno. El experimento dio resultado y los científicos corroboraron que los ratones del grupo experimental no desarrollaron asociabilidad. En efecto, se puso a prueba a los animales con diversos ejercicios. Uno de ellos consistía en, dentro de una estructura de laberinto, elegir un camino donde había un objeto y otro donde había otro animal. Los ratones, como era de esperarse en condiciones normales, eligieron el camino donde había otro ser vivo. También se puso a prueba a los ratones del experimento con los de control haciéndolos interactuar entre sí.

«Ahora falta entender qué pasó y por qué», dice Depino sobre este trabajo, ya que aún se desconoce el mecanismo por el cual sucede, aunque hay una línea de investigación ya abierta. «Usando un tomógrafo de pequeña escala vimos una región cambios en una región, la corteza piriforme, que no estaba siendo muy estudiada y que podría tener implicancias en el desarrollo de la conducta autista», concluye Depino.

Fuente: https://www.infotechnology.com/

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Metán

Increíble: En Metán, un joven fue condenado a dos años de prisión por nueve delitos

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Un joven de 22 años fue condenado por ser autor de los delitos de evasión; hurto calificado; hurto con escalamiento y violación de domicilio en concurso real; hurto calificado, robo y hurto en concurso real; robo y hurto calificado; y cumplirá la pena de tan solo dos años de prisión de ejecución condicional, y tendrá prohibido acercarse y contactarse con las víctimas. Deberá además realizar tratamiento psicológico.

La Oficina de Gestión Judicial (OfiJu) de Metán fijó una audiencia flexible y multipropósito en el marco del plan piloto de oralidad, durante la cual el juez de Garantías Mario Dilascio escuchó a las partes, que dijeron haber arribado a un acuerdo de juicio abreviado, para lo cual se acumularon cinco expedientes de trámite ante diferentes tribunales de Metán.

 

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Salta

Milei recibe a Sáenz y a gobernadores en la Rosada

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El presidente Javier Milei presentará este martes a los gobernadores provinciales su propuesta para derogar las Primarias, Abiertas, Simultáneas y Obligatorias (PASO) e implementar la Boleta Única de papel.

Así lo señalaron a la agencia Noticias Argentinas fuentes de Casa Rosada, antes del encuentro que este martes encabezará el jefe de Estado con los 23 gobernadores y el jefe de Gobierno porteño, Jorge Macri, en Casa Rosada.

El ministro del Interior, Guillermo Francos, había anticipado la iniciativa en un encuentro que tuvo la semana pasada con la Cámara Nacional Electoral (CNE).

La duda del Gobierno está en avanzar a través de un proyecto que se encuentra en la Cámara de Diputados con media sanción o si envía uno propio.

Lo que busca el Presidente es eliminar las primarias y establecer la Boleta Única Papel para reformar el sistema electoral argentino en 2024, aprovechando que varios gobernadores también quieren desterrar las PASO y que no será un año electoral.
Fuente: El Liberal

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Sin categoría

Rosario de la Frontera: Gime Millán representará al país en México

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La rosarina Gime Millán, con mucho esfuerzo y dedicación logro clasificar en el Sudamericano de Padel y representará a nuestro país en México.

«Muchas gracias a mi compañera por este tremendo torneo que se mandó, por su esfuerzo y por lograr sacar juntas cada partido. Gracias a todas las personas que nos acompañaron, cerca o lejos esas fuerzas me llegaron. Clasificamos al Sudamericano en México y eso me pone muy feliz. «A seguir Salta en lo más alto» compartió la deportista en sus redes sociales.

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